Resolving postoperative neuroinflammation and cognitive decline
نویسندگان
چکیده
منابع مشابه
P147: Postoperative Cognitive Dysfunction and Neuroinflammation Associated with Cardiac Surgery
One of the incapacitating postoperative morbidities that was seen in all types of surgery is Postoperative cognitive dysfunction (POCD). The elder patients and also cardiac surgery patients (CSPs) are at particular risk. Additionally it was shown that the severity, extension of impairment and the incidence rate of POCD is more in CSPs. POCD is a dementia-like symptoms disorder is characterized ...
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Significant advances in medical science during the last century have resulted in a gradual, but highly significant, increase in human life span. On the surface this is a great achievement, but as people age, their cognitive function is threatened by the normal aging process, as well as increasing risk for dementia.1 The precise cause of the neuronal degeneration underlying these disorders, and ...
متن کاملP100: A Review of Postoperative Cognitive Dysfunction and Neuroinflammation Processes Induced by Anaesthesia
Although anaesthesia is generally effective, safe and also an indispensable preoperative clinical approach, there is a really growing concern about usage, form of usage and dosage of it. Postoperative cognitive dysfunction (POCD) is one of the common postoperative complications that often affects elderly patients and includes a range of domains, may involve oxidative stress and neuroinflammatio...
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T AU is an axonal microtubule-associated protein whose best known function is to bind and stabilize microtubules and promote their polymerization. Tau, a variously sized protein, has a number of repeated domains that bind tubulin and a number of phosphorylation sites that modulate its affinity for tubulin. In general, phosphorylation through a number of kinases decreases tau affinity to microtu...
متن کاملIs postoperative cognitive decline clinically relevant?
To the Editor: We applaud Avidan et al. in their assessment of the general relationship between postoperative cognitive dysfunction (POCD) and dementing illness. We have a number of questions and concerns, and we hope the authors might address them. As noted by the authors, the report revisits the question of whether geriatric patients who undergo surgery have a more rapid decline into dementia...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2011
ISSN: 0364-5134
DOI: 10.1002/ana.22664